Comparison of systemic immune-inflammation index (SII), early warning score (ANDC) and prognostic nutritional index (PNI) in hospitalized patients with malignancy, and their influence on mortality from COVID-19

Abstract Introduction We evaluated several biological indicators based on inflammation and/or nutritional status, such as systemic immune-inflammation index (SII), early warning score (ANDC) and prognostic (PNI) in hospitalized COVID-19 patients with without malignancies for a significance. Methodology This is retrospective observational study 186 SARS-CoV-2, who were diagnosed by real-time PCR testing due to pneumonia. 75 had various malignancies, the rest (111), having similar age comorbidity profile propensity matching, no malignancy. Results None of measures neutrophil lymphocyte ratio, platelet monocyte SII, PNI or ANDC was found be significantly different between two groups. Odds ratio mortality, OR 2.39 (%95 CI 1.80–3.16) higher malignancy group, even though duration hospitalization statistically both lower deceased compared survivors group. Contrarily, Conclusions have independent predictive power determining in-hospital death cases. It suggested that seems more sensitive than SII cases malignancies.